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Brian Mazanec is a Deputy Assistant Secretary and Director of the Center for the HHS Coordination Operations and Response Element (H-CORE) and the Acting Director of the Center for Preparedness within the Administration for Strategic Preparedness and Response (ASPR).
H-CORE's mission today is to lead and enable agile, data-driven operational coordination, logistics readiness, and scalable response for public health emergencies and disasters, including infectious disease outbreaks and cyber attacks. ASPR’s Center for Preparedness helps advance a full range of preparedness activities for public health emergencies and disasters, including leading the Medical Reserve Corps, National Special Pathogen System, HHS continuity of operations and continuity of government activities, and departmental planning and exercises. Prior to his current role, Brian served as Deputy Director of the ASPR Center for Preparedness and the Deputy Assistant Secretary for Security, Intelligence, and Information Management.
Prior to joining ASPR, Brian served at the U.S. Government Accountability Office (GAO), where he was the senior executive responsible for leading the agency’s Strategic Warfare and Intelligence portfolio. He led and managed numerous teams evaluating a variety of national security programs and activities related to biological and other emerging threats; intelligence community management; security and counterintelligence; sensitive activities and programs; personnel vetting; and space policy and operations. Brian also previously worked on Weapons of Mass Destruction (WMD) issues at the Defense Intelligence Agency, Office of the Deputy Assistant Secretary of Defense for Nuclear Matters, and the Joint Staff J5 Combating WMD directorate.
Brian received his PhD in Biodefense from George Mason University’s Schar School of Policy and Government and holds a BA in political science from the University of Richmond and a MS in defense and strategic studies from Missouri State University’s Department of Defense and Strategic Studies. In addition to his work in government, Brian’s teaches graduate level courses at several local universities, and he has authored or co-authored multiple academic books on cyber issues. He lives in Falls Church, Virginia with his wife and four children.
