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COVID-19 Therapeutics Thresholds, Orders, and Replenishment by Jurisdiction

On April 25, 2022, the distribution process for COVID-19 therapeutics to state and territorial health departments transitioned from the previous allocation process to one that more closely aligns with the allocation and ordering process for vaccines. This process, known as the threshold and replenishment method, offers sites identified by state and territorial health departments the ability to order product seven days a week through the Health Partner Ordering Portal (HPOP). The federal government tracks the amount of COVID-19 therapeutic products ordered by sites each week.

On Mondays, the federal government replenishes state and territorial health departments with an amount of product equal to the amount ordered by sites the previous week. This replenishment method ensures that the total amount of product available to jurisdictions each week is consistent, and this amount is known as a jurisdiction’s threshold quantity.

Threshold quantities are determined using the same methodology as previous allocations: Paxlovid and Lagevrio threshold amounts are determined on a pro rata population basis, and Bebtelovimab threshold amounts are determined using a disease-based methodology. Evusheld threshold amounts are determined on a pro rata population basis and replenishment occurs monthly.

Requests for additional product can be made by state and territorial health department officials at any time if a jurisdiction’s current supply is not sufficient to meet demand.

The tables below provide a summary of the total product threshold amounts and other information relative to product ordering and administration. Select a date to view the threshold, order, and replenishment summary for states, territories, federal entities and pharmacy partners.

COVID-19 Therapeutics Summary: For All Open Distribution Channels1

December 17, 2021 – November 27, 2022

Therapeutic Courses Delivered Courses Administered2
Paxlovid3 9,020,933 5,970,167
Lagevrio 2,586,880 Under Review
Bebtelovimab 739,471 618,588
Evusheld (300mg doses) 989,496 659,372
Total:
View Data by Jurisdiction
13,336,780 7,248,127

1States, territories, and federal entities, including HRSA
2Based on 91% of sites reporting as of November 27, 2022
3Includes Paxlovid and Renal Paxlovid
Data source: HHS-Tiberius

COVID-19 Therapeutics Summary: Previously Distributed Products

November 2020 – April 14, 2022

Therapeutics
(currently not in use)
Courses Delivered Courses Administered
REGEN-COV 2,878,138 2,078,587
Bamlanivimab/Etesevimab 642,125 610,753
Sotrovimab 706,692 302,209

COVID-19 Therapeutics Threshold Determinations

April 25, 2022 – December 11, 2022

Paxlovid
(Standard and Renal)
Lagevrio
(molnupiravir)
Bebtelovimab Evusheld Total
December 5-December 11, 2022 613,580 48,735 - 204,096 866,411
November 28-December 4, 2022 612,060 48,240 - 0 660,300
November 21-November 27, 2022 612,060 48,240 - 0 660,300
November 14-November 20, 2022 612,060 48,240 - 0 660,300
November 7-November 13, 2022 612,060 48,240 - 0 660,300
October 31-November 6, 2022 613,580 48,735 - 204,096 866,411
October 24-October 30, 2022 612,060 48,240 - 0 660,300
October 17-October 23, 2022 612,060 48,240 - 0 660,300
October 10-October 16, 2022 612,060 48,240 - 0 660,300
October 3-October 9, 2022 613,580 48,735 - 204,096 866,411
September 26-October 2, 2022 612,060 48,312 - 0 660,372
September 19-September 25, 2022 612,060 91,920 - 0 703,980
September 12-September 18, 2022 612,060 91,920 - 0 703,980
September 6, 2022: Bebtelovimab Final Allocation - - 19,500 - 19,500
September 5-September 11, 2022 612,060 91,920 - 0 703,980
August 29-September 4, 2022 613,580 92,352 0 203,736 909,668
August 22-August 28, 2022 612,060 91,920 21,915 0 725,895
August 15-August 21, 2022 612,060 91,920 29,060 0 733,040
August 8-August 14, 2022 612,060 91,896 29,110 0 733,066
August 1-August 7, 2022 612,260 92,328 29,760 203,760 938,108
July 25-July 31, 2022 610,340 91,896 29,190 0 731,426
July 18-July 24, 2022 642,695 113,368 29,250 0 785,313
July 11-July 17, 2022 596,955 114,400 29,200 0 740,555
July 4-July 10, 2022 575,715 114,856 29,210 0 719,781
June 27-July 3, 2022 590,085 114,576 28,710 201,168 934,539
June 20-June 26, 2022 579,120 109,896 28,985 0 718,001
June 13-June 19, 2022 405,084 71,664 29,060 0 505,808
June 6-June 12, 2022 444,225 92,828 29,140 240 566,433
May 30-June 5, 2022 459,638 100,820 29,630 200,808 790,896
May 23-May 29, 2022 473,106 115,960 29,100 0 618,166
May 16-May 22, 2022 463,417 105,036 29,040 0 597,493
May 9-May 15, 2022 386,965
107,208 29,110 0 523,283
May 2-May 8, 2022 348,160 108,920 29,000 199,992 686,072
April 25-May 1, 2022 386,700 177,120 30,000 0 593,820

Prior Distribution Efforts

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