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API Innovation Center (APIIC)

ASPR's IBx Portfolio


Location: St. Louis, MO 

Product: Albuterol, Metoprolol Succinate, Lorazepam, Propofol

Description of Project: Modernize manufacturing capacities at each of the non-profit coalition members (MilliporeSigma, University of Missouri – St. Louis, and Mallinckrodt Pharmaceuticals) via implementation of novel manufacturing processes and technologies to provide end-to-end domestic supply chains for all key starting materials and active pharmaceutical ingredients used to produce three (3) priority essential medicines  

Unique Impact: Use of advanced manufacturing technologies using all domestic inputs 

Base Award Amount: ​$13,968,691

Year Awarded: October 2024

Projected Drug Master File (DMF) Filing Date: December 2026.

Category: KSM/API and FDF