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ASPR Announces New Notice of Funding Opportunity (NOFO) for Regional Emerging Special Pathogen Treatment Centers (RESPTCs)

The U.S. Department of Health and Human Services (HHS), Administration for Strategic Preparedness and Response (ASPR) is pleased to announce a new Notice of Funding Opportunity (NOFO) for the Regional Emerging Special Pathogen Treatment Center (RESPTC) Cooperative Agreement. 

The purpose of this NOFO is to sustain and improve health care system preparedness for emerging special pathogens through implementation of the National Special Pathogen System of Care Strategy  and to expand the regional hospital network within the National Special Pathogen System. As regional hubs for special pathogen readiness, RESPTCs are a resource for patient care and clinical operations among the region’s health care organizations. Additionally, RESPTCs mitigate surges of patients at health care facilities through supporting patient distribution across the region.

Through the Fiscal Year (FY) 2022 Consolidated Appropriations Act explanatory language, Congress directed ASPR to “increase the overall number of RESPTCs by at least three Centers.[1] To meet this requirement, ASPR received funding to sustain the 10 existing RESPTCs and add three new sites, expanding the total number of RESPTCs from 10 to 13. In consideration of these changes, ASPR will close out the existing Hospital Preparedness Program (HPP) Ebola Preparedness and Response Activities project period and expand the RESPTC program through a new, two-part NOFO: Part A provides awards to the existing 10 RESPTCs and Part B, through a competitive award process, provides funding for three new sites.

Applications will be due at 5:00 PM ET on September 22, 2022.

Technical Assistance Call

During this meeting, ASPR held a technical assistance call for interested applicants and potential applicants to learn more about this funding opportunity. The audio recording and transcript are accessible to view below.


Audio Recording​ | Transcript​



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