Disposal of Expired TPOXX
TPOXX (Tecovirimat) Operational Planning Guide — Information for Providing Therapeutics for Persons with Mpox
At this time, there are no anticipated expiry date extensions for oral TPOXX, and some lots of oral TPOXX deployed during the mpox response began expiring in March 2023. Once oral TPOXX is expired, jurisdictions may dispose of the product using their own established protocols for disposal. Information on safe disposal of medicines is available on the
- Jurisdictions are expected to maintain records of lot numbers and quantities of products that are destroyed. Wastage records should be entered into HPOP.
- While there are currently no anticipated dating extensions for oral TPOXX, jurisdictions are free to hold expired product in quarantine if they choose to do so.
- IV TPOXX may be eligible for expiration extension, and jurisdictions are strongly encouraged to continue storing IV TPOXX even beyond current expiration dates. As more information becomes available, the dating will be updated on the website. These products are important for maintaining preparedness for future mpox outbreaks, and other orthopoxvirus outbreaks or responses.