Readiness Checklist

ASPR/CDC Mpox Vaccination Operational Planning Guide - HHS Mpox Vaccination Program

The following checklists are to facilitate jurisdiction readiness for HHS distributed supply.

Determine which provider locations will receive initial vaccine supply, balancing equitable access with vaccination capacity, cold chain management capabilities, and consideration of initial demand.
With the current expanded distribution capability for JYNNEOS, jurisdictions may designate as many distribution sites as required.
Plan to receive at central locations where possible for vaccine management and local redistribution, as applicable, within their jurisdiction.
Plan for prompt return of cold chain shipping containers and temperature monitoring devices using provided shipping labels.
Review CDC and manufacturer materials regarding product configuration, shipping, storage, dosing, dosing intervals, and adverse event profiles.
Optimize vaccine use by ordering additional supply responsibly to minimize unnecessary accumulation of inventory and wastage while also ensuring no vaccination opportunity is missed.

Employ inventory management practices, including accurately reporting on-hand product inventory to inform tracking near-expiry and redistribution.
Manage and accurately report on-hand product inventory to inform tracking near-expiry and redistribution.
Report vaccine administration data.

Identify an adequate network of providers to ensure equitable expansion across populations at high risk for infection:

Identify providers and facilitate their participation, especially providers who can fill a geographic or underrepresented population gap in access.
Include clinical venues that serve people who have historically had less access to primary care, for example sexual health or STD clinics, LGBTQ+ health clinics, and pharmacies.
Identify and facilitate enrollment of providers who frequently care for individuals with disabilities or special healthcare needs (e.g., HIV+).
Identify and facilitate enrollment of providers who frequently care for individuals with disabilities or special healthcare needs (e.g., HIV+).
Reach out to tribal nations within the respective areas for involvement in planning efforts.

Develop a plan to identify if or when additional sites may be needed, especially during the initial weeks of the vaccination program when demand may be high.
Disseminate training and communication materials to healthcare providers (e.g., fact sheets, online videos).
Remind enrolled providers to prepare scheduling systems and bolster capacity for their call center and website, as needed, to handle additional volume.
Ensure second doses are requested in a timely manner in order to complete the two-dose series of JYNNEOS.
Ensure providers or other on-location staff are equipped and trained to respond to possible severe allergic reactions.
Jurisdictions should onboard delivery locations to align with expanded distribution capacity.

Maintain unused vaccine doses at appropriate temperatures to maximize storage life.
Reinforce providers are required to report certain adverse events following vaccination to the Vaccine Adverse Event Reporting System (VAERS).

Any adverse event listed in the VAERS Table of Reportable Events Following Vaccination that occurs within the specified time period after vaccinations.
An adverse event listed by the vaccine manufacturer as a contraindication to further doses of the vaccine
Adverse events following administration of JYNNEOS as specified in the Emergency Use Authorization here, as well as the HHS Provider Agreement as listed
Vaccine administration errors, whether or not associated with an adverse event

Any additional clinically significant adverse event that occurs after the administration of a vaccine, whether it is or is not clear that a vaccine caused the adverse event.

Routinely evaluate the adequacy of the provider network, identifying gaps and whether additional vaccination locations (e.g., local public health departments, Federally Qualified Healthcare Centers [FQHCs], other program clinics such as STD/HIV clinics) may be needed to further increase equitable access and ensure vaccine equity.

Leverage Health Partner Ordering Portal (HPOP) for jurisdictions and federal entities to order vaccines for provider sites.
Report vaccine inventory, utilization, and wastage through HPOP.
Ensure electronic systems, including IISs, are reporting and tracking vaccine administration.
Once the vaccination program begins, continue to leverage Tiberius dashboards to monitor the program.

Create a communication plan that outlines strategies, audiences, and products that will be used to promote vaccination in high-risk individuals.
Understand existing data on knowledge, attitudes, and perceptions regarding vaccination in terms of demand, provider types, and locations where vaccination would be preferred. Share these data with local jurisdictions and partners to help shape messages.
Develop communications products for providers and the public that align with federal messaging and ensure communication materials are culturally and linguistically appropriate.
Leverage partnerships to help mobilize providers and promote vaccination messaging.
Engage and educate partners and trusted messengers (e.g., healthcare professionals, community leaders) as soon as possible.

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