Delivery Locations

Locations receiving HHS distributed vaccine need to be ready to maintain the cold chain and meet other storage and handling requirements. Jurisdictions should create a distribution plan in coordination with local health departments and other partners, and carefully determine which sites will receive vaccine product, incorporating the considerations listed below.

• ​Ordering locations must be registered in HPOP.
• Jurisdictions may designate as many distribution sites as required. The recipient should coordinate with staff familiar with handling and storing temperature-controlled pharmaceuticals.
• The recipient must open shipping containers and follow the enclosed instructions to immediately stop temp-tale to validate sustained shipping temperature range.​
  
• HPOP mpox MCM orders and shipments:
• Temp-tale deviation information/picture must be sent back to sns.ops@h​hs.gov.
• SNS will evaluate the temp-tale picture (for deviations) and give the go-ahead by email that the product is usable.
• Immediately return the shipping container/s and the temp-tale/s to SNS using the provided shipping label.
• If there are any issues or concerns with the received product, please notify SNS at sns.ops@hhs.gov immediately.
• JYNNEOS should be given as a 2-dose vaccine series. Providers are responsible for the appropriate management of opened vials of JYNNEOS necessary to administer second doses of JYNNEOS.
• HHS and the manufacturer(s) offer additional training to prepare providers to administer ACAM2000 vaccine; providers will need to be trained.
• CDC offers healthcare providers and vaccine administrators the information they will need to learn how to administer the ACAM2000 smallpox vaccine using the multiple-puncture technique and a bifurcated needle:  Administering ACAM2000 Smallpox Vaccine Videos | Smallpox | CDC